Injecting Water onto a GC Column: Solving the Mystery of …

The large expansion volume of water can cause backflash, carryover can cause inconsistent results, and excess water can extinguish the flame ionization …

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Poly(ethylene glycol) alternatives in biomedical applications

Poly(ethylene glycol) (PEG) as gold standard has been extensively conjugated to diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is known as PEGylation. After the PEGylation, these formations are expected to achieve superior diagnostic and therapeutic effects. However, in-depth …

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Poly(ethylene glycol)-mediated mineralization of metal …

Affiliations 1 Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China. [email protected].; 2 School of Physics and Electronic Science, East China Normal University, Shanghai 200241, China. …

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SOP 109 – Ethylene Glycol Screen by Gas …

1.2. Ethylene glycol is completely miscible with water, and as such is extremely difficult to remove from blood and serum samples. This procedure describes a method which extracts the ethylene glycol present in blood or serum, such that it can be easily derivatized and identified by gas chromatography/mass spectrometry. 2. Specimens 2.1.

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SAFETY DATA SHEET

SAFETY DATA SHEET Creation Date 02-Feb-2010 Revision Date 24-Dec-2021 Revision Number 5 1. Identification Product Name Ethylene glycol No. : E177-4; E177-20 CAS No 107-21-1 Synonyms Monoethylene glycol; 1,2-Ethanediol Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product …

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GC-MS Analysis of Diethylene Glycol and Ethylene …

62 for ethylene glycol, m/z 75 for diethylene glycol and m/z 58 for 1,3-propane diol. The FDA method applies a formula to obtain the estimate for a semi-quantitative analysis for target analytes. In this case, Xcalibur software was used to calculate the spiked samples against the high

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Ethylene Glycol Toxicosis in Animals

Ethylene glycol is rapidly absorbed from the gastrointestinal tract, with peak absorption in 1–4 hours and a serum half-life of 3 hours. Approximately 50% of ingested ethylene glycol is excreted unchanged by the kidneys; however, a series of oxidation reactions in the liver and kidneys metabolizes the remaining ethylene glycol.

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GC Analysis of Glycols and Diols

Glycol and diol compounds are used to solubilize active ingredients for use in many consumer products, including cosmetics, ballpoint pen inks, wood stains, and lacquers.

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Ethylene Glycol

A person could be exposed to ethylene glycol through skin contact when using automobile antifreeze. According to the U.S. Centers for Disease Control (CDC), skin contact with a very small amount of ethylene glycol in conditions like these "will not affect your health." 1 Ethylene glycol can be poisonous if ingested. Many states now require …

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Toxicological Profile for Ethylene Glycol

ETHYLENE GLYCOL 207 7. ANALYTICAL METHODS The purpose of this chapter is to describe the analytical methods that are available for detecting, measuring, and/or monitoring ethylene glycol, its metabolites, and other biomarkers of exposure and effect to ethylene glycol. The intent is not to provide an exhaustive list of analytical methods.

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Ethylene glycol: properties, synthesis, and …

A review article on ethylene glycol (EG), a versatile chemical intermediate derived from fossil fuels and biomass resources. It covers the physical …

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Engineering Pseudomonas putida KT2440 for efficient ethylene glycol

1. Introduction. Ethylene glycol is a large-volume industrial chemical used for myriad applications including for the production of polyester plastics such as polyethylene terephthalate (PET), as a coolant in antifreeze, as a deicing fluid for aircraft, and as an inhibitor of clathrate hydrate formation in natural gas pipelines (Harris, 2013, Yue et al., …

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Ethylene glycol: an estimate of tolerable levels of exposure …

Upon ingestion ethylene glycol (EG, monoethylene glycol) is rapidly absorbed from the gastrointestinal tract, and depending on the severity of exposure signs of toxicity may progress through three stages. Neurological effects characterize the first step consisting of central nervous depression (into …

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Ethylene glycol

Physicochemical properties of ethylene glycol. Ethylene glycol with the formula CH 2 OH 2, also known as 1,2-ethanediol, is a popular organic compound.The safety data sheet for ethylene glycol, as well as for other substances, is the primary source of information on their physical and chemical properties. Ethylene glycol is the main …

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Protein encapsulation into biodegradable microspheres by a …

Putney et al. reported that spray-freeze-dried microparticles with a single-micron size (preferably under 5 μm) of human growth hormone could be useful intermediates for microencapsulation by S/O/W emulsion [10].This may be due to the good dispersion characteristics of such small microparticles in the organic phase.

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ETHYLENE GLYCOL | CAMEO Chemicals | NOAA

Ethylene glycol: 107-21-1: Liquid >480 >480 >480 >480 >480 >480 >480: Glycol alcohol: 107-21-1: Liquid >480 >480 >480 >480 >480 >480 >480 > indicates greater than. Special Warning from DuPont: Tychem® and Tyvek® fabrics should not be used around heat, flames, sparks or in potentially flammable or explosive environments. Only...

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A Case of Ethylene Glycol intoxication with Acute Renal …

Introduction. Ethylene glycol is a colorless, odorless, and water-soluble substance. It is currently used as a raw material in solvents, antifreezes, diluents, and various chemicals1).It is referred to as a "sweet killer" in the West because it is sweet and does not irritate the oral mucosa when ingested2).Ethylene glycol poisoning often …

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Engineering Pseudomonas putida KT2440 for efficient ethylene glycol …

Ethylene glycol is used as a raw material in the production of polyethylene terephthalate, in antifreeze, as a gas hydrate inhibitor in pipelines, and for many other industrial applications. It is metabolized by aerobic microbial processes via the highly toxic intermediates glycolaldehyde and glycolate through C2 metabolic pathways. …

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Treatment of Ethylene Glycol Poisoning

Ethylene glycol is a solvent found in products ranging from antifreeze fluid and de-icing solutions to carpet and fabric cleaners. 3, 4 According to results from animal studies, 4 the ingested ...

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What Are the Toxicological Effects of Ethylene Glycol Poisoning?

A three-stage theory of ethylene glycol poisoning was introduced in the 1950s (Berman et al. 1957; Kahn and Brotchner 1950). These stages are theoretical descriptions of ethylene glycol poisoning, but the onset and progression of the clinical course is frequently not consistent or predictable.

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Ethylene glycol | Properties, Uses, & Structure

Ethylene glycol is highly poisonous; animals or humans that drink the solution become very ill and may die. In addition to its use in antifreeze, ethylene glycol is used as an ingredient in hydraulic fluids, …

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Methanol and ethylene glycol poisoning: Management

Methanol and ethylene glycol poisonings cause scores of fatal intoxications annually, and even relatively small ingestions of these alcohols can produce significant toxicity. Rapid recognition and early treatment, including alcohol dehydrogenase (ADH) inhibition and often hemodialysis, are crucial.

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Ethylene Glycol | Public Health Statement | ATSDR

Ethylene glycol is a synthetic liquid substance that absorbs water.� Ethylene glycol is used to make antifreeze and de-icing solutions for cars, airplanes, and boats.� It is an ingredient in hydraulic brake fluids and in inks used in stamp pads, ballpoint pens, and print shops.� It is a solvent used in the paint and plastics industry, and is used to produce …

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Ethylene glycol poisoning: a rare but life-threatening cause …

The initial diagnosis of ethylene glycol poisoning is difficult and poisoning with ethylene glycol is rare but life threatening and needs rapid recognition and early treatment. Therefore, intoxication with ethylene glycol should not be misdiagnosed as lactic acidosis in patients with metabolic acidosis and elevated lactate levels.

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Micronization of polyethylene glycol by PGSS (Particles …

DOI: 10.1016/J.CEP.2010.09.014 Corpus ID: 96776774; Micronization of polyethylene glycol by PGSS (Particles from Gas Saturated Solutions)-drying of aqueous solutions @article{Martn2010MicronizationOP, title={Micronization of polyethylene glycol by PGSS (Particles from Gas Saturated Solutions)-drying of aqueous solutions}, …

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Protein encapsulation into biodegradable microspheres by …

Incubation of these pastes at 37°C, surrounded by aqueous fluid leads to thermoresponsive liquid sintering and the formation of porous solid constructs [22][23][24][25][26][27].

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Selective production of ethylene glycol at high rate via …

To demonstrate the sustainable production of ethylene glycol, we developed an integrated system to produce ethylene glycol from CO 2 directly instead of from …

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14.6: Glycols and Glycerol

Ethylene glycol is the main ingredient in many antifreeze mixtures for automobile radiators. The two OH groups lead to extensive intermolecular hydrogen bonding. This results in a high boiling point—198°C; thus ethylene glycol does not boil away when it is used as an antifreeze. It is also completely miscible with water.

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GC Analysis of Glycols in Toothpaste

Common moisturizers and sweeteners in toothpaste are propylene glycol, sorbitol, and glycerin. Diethylene glycol (DEG) is an organic solvent often used in antifreeze [1,2], and …

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A new-to-nature carboxylation module to improve natural …

We verified our active-site redesign with an atomic-resolution, 1.96-Å cryo-electron microscopy structure and engineered two more enzymes that, together with GCC, form a carboxylation module...

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How Should Patients Exposed to Ethylene Glycol Be Treated …

serum ethylene glycol levels exceed 50 mg/dL (8.1 mmol/L), severe acidemia (pH <7.25) or fluid/electrolyte disturbances persist despite ethanol or fomepizole therapy, vital signs continue to deteriorate despite intensive supportive treatment, or; renal failure develops.

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Ethylene glycols

Shell Chemicals produces ethylene glycols (MEG, DEG, TEG) for various applications, such as polyester, antifreeze and plasticisers. Learn more about Shell's global leadership in ethylene glycols and ethylene oxide …

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